Abesifazane, ngokushesha noma kamuva, bahlushwa ukungabi khona kokuya esikhathini. Lesi sigaba esisha sibizwa ngokuthi ukunqamuka kokuya esikhathini futhi, kuze kube namuhla, akukaze kwenzeke ukuthi kubonakale ukuthi kuzokwenzeka nini. Kwenzeka nje, futhi abesifazane balinda umzuzwana.
Ukunqamuka kokuya esikhathini kuletha izinguquko ezinkulu zamahomoni, ezithinta kokubili izinga lokushisa komzimba, impilo engokomzimba nengokwengqondo. Manje, ucwaningo lwakamuva luhlonze ukuhlukahluka kofuzo okucishe kube ngu-300 okuthonya iminyaka yabesifazane ekunqamukeni kokuya esikhathini. Ithimba labacwaningi e-University of Exeter (UK) lithole ukuthi lezi zinhlobonhlobo zofuzo zingabikezela cishe iminyaka yobudala lapho abanye besifazane bezoyeka ukuya esikhathini futhi bahlonze labo abasengozini yokunqamuka kokuya esikhathini ngaphambi kwesikhathi.
Imiphumela ingase iholele ekwelashweni okungcono kakhulu kokungatholi abantwana esikhathini esizayo futhi yandise iminyaka yokuphila yemvelo yokuzala yabesifazane. Abacwaningi baphinde bahlola imiphumela ethile yezempilo yokuba nokunqamuka kokuya esikhathini ngaphambi kwesikhathi noma kamuva. Bakuthola ngokofuzo lokho ukunqamuka kokuya esikhathini kwangaphambi kwesikhathi kwandisa amathuba okuba nesifo sikashukela sohlobo 2 futhi yayixhunyaniswe nempilo ebuthakathaka yamathambo kanye nengozi enkulu yokuphuka. Kodwa bathola ukuthi ukunqamuka kokuya esikhathini ngaphambi kwesikhathi kwehlisa amathuba okuba nezinhlobo ezithile zomdlavuza, njengomdlavuza wesibeletho nowebele.
Ngokungangabazeki, le miphumela izovula amathuba amasha okusiza abesifazane ukuhlela ikusasa. Ngokuthola ezinye izimbangela eziningi zofuzo zokuhlukahluka esikhathini sokunqamuka kokuya esikhathini, kuye kwaboniswa ukuthi umuntu angaqala bikezela ukuthi yibaphi abesifazane abangase babe nokunqamuka kokuya esikhathini ngaphambi kwesikhathi ngakho-ke kunzima ukukhulelwa ngokwemvelo. Kumele kukhunjulwe ukuthi bonke abesifazane bazalwa ngokuhlukahluka kofuzo, ngakho-ke icala ngalinye likhethekile futhi liyingqayizivele.
I-Genetics ingabambezela ukuya esikhathini ngeminyaka engu-3
Ocwaningweni, abacwaningi bahlaziye idatha yofuzo eqoqwe kwabesifazane base-Europe naseMpumalanga Asia base-UK Biobank, enolwazi lwezempilo nofuzo kubantu abangaba yingxenye yesigidi. Baphinde basebenzisa amagundane angamamodeli ukuhlola imiphumela yezinye zezakhi zofuzo ekuphileni kokuzala kwamagundane.
Kulezi zilwane, abacwaningi bathola izakhi zofuzo ezimbili, i-Chek1 ne-Chek2, ezithinta i- inzalo kanye neminyaka yokuphila kokuzala. Ithimba lithole ukuthi ukukhipha i-Chek2 ukuze ingasasebenzi ngenkathi i-Chek1 iveza ngokweqile ukuthuthukisa umsebenzi kwandisa isikhathi sokuphila sokuzala kumagundane cishe ngamaphesenti angu-25.
Kunalokho, abesifazane ngokwemvelo ukuntula isakhi sofuzo se-Chek2 esisebenzayo, ososayensi bathola lokho ukufinyelela menopause Eminyakeni engu-3,5 kamuva kunabesifazane abanofuzo olusebenza ngokujwayelekile.
USolwazi u-Eva Hoffmann, waseNyuvesi yaseCopenhagen, naye ongumbhali-nhlangano walolu cwaningo, uthe abakutholile "ukunikeza isiqondiso esisha esingaba khona sezindlela zokwelapha ezingase zifune ukwelapha ubunyumba, ikakhulukazi ekwelapheni ukukhulelwa kwe-in vitro".
Waphawula ukuthi: «La ukukhulelwa kwe-in vitro Isekelwe ekugqugquzelweni kwe-hormonal kwabesifazane. Sithole ukuthi kwenye yamamodeli ethu egundane, i-Chek2, abesifazane babenempendulo ethuthukisiwe ekushukunyisweni kwama-hormone, okusho ukuthi kwatholwa amaqanda engeziwe ukuze zelashwe ngempela. ukukhulelwa kwe-in vitro. LOkuboniswa yizifundo zethu ukuthi kungenzeka ukuthi ukuvimbela okuhlosiwe kwesikhashana kwalezi zindlela phakathi nokwelashwa kwe-IVF kungasiza abanye besifazane ukuba baphendule kangcono.".